CT Perfusion
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Interpretation
- Infarct: Increased MTT, decreased CBF, decreased CBV
- Penumbra: Increased MTT, decreased CBF, maintained CBV
- Good reference article for CT Perfusion StrokeCT.pdf
From Radiographics article above.
- MTT/TTP most sensitive, but least specific. Can look here first for subtle abnormalities, then see if real on CBV/CBF (CBF most spec).
- decreased CBV = correlate of restricted diffusion on MRI
- If no abnormal CBV, but decreased CBF then hypoperfused without infarct (e.g. high grade stenosis).